What are biomarkers and what are they used for

The patients immune system is programmed to recognize issuses within itself or foreign. The goal of biomarkers is to identify a problem early in the process when things can be done to prevent permanant damage to the transplanted kidney.
What is an RNA signature, and how can it help in identifying acute rejection?

Biology of Graft Rejection & Damage

For patients undergoing kidney transplantation, there are many risks from both within the body and from external threats that may result in rejection, injury, or failure of the graft and jeopardize patient outcomes. These risks relate to many different biological pathways and systems at play within our bodies. The immune system is the most well recognized risk. Because it is designed to monitor and attack invading foreign elements to protect the body, it is not able to distinguish that the transplanted kidney is there to help...
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